Comparison of Microneedles and Adhesive-Tape Stripping in Skin Preparation for Epicutaneous Allergen Delivery

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Comparison of microneedles and adhesive-tape stripping in skin preparation for epicutaneous allergen delivery.

BACKGROUND Epicutaneous immunotherapy targets the network of dendritic cells in the epidermis. Allergen exposure of the dermal layers should be limited as these contain mast cells and blood vessels, which increases the risk for local and systemic allergic reactions. METHODS This intraindividually controlled trial included 20 subjects with birch pollen allergy. Three areas of the volar forearm...

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Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunotherapy.

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Interpretation of the human skin biotribological behaviour after tape stripping.

The present study deals with the modification of the human skin biotribological behaviour after tape stripping. The tape-stripping procedure consists in the sequential application and removal of adhesive tapes on the skin surface in order to remove stratum corneum (SC) layers, which electrically charges the skin surface. The skin electric charges generated by tape stripping highly change the sk...

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ژورنال

عنوان ژورنال: International Archives of Allergy and Immunology

سال: 2015

ISSN: 1018-2438,1423-0097

DOI: 10.1159/000434681